DMPQ: Write down the difference between antigen and antibodyand their role in vaccine development.


  Antigen Antibody
Overview Substance that can induce an immune response Proteins that recognize and bind to antigens
Molecule type Usually proteins, may also be polysaccharides, lipids or nucleic acids Proteins
Origin Within the body or externally Within the body


The Role of Antigens & Antibodies in Vaccinations

Vaccines contain antigens which stimulate the B lymphocytes of the immune system to respond by producing plasma cells which secrete disease specific antibodies (Primary response). Some of the B cells become memory B cells, which will recognise future exposure to the disease. This results in a faster and more intense production of antibodies, which effectively work to eliminate the disease by binding to the antigens (Secondary response).

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